The first round is split into North and South. There is no regionalisation in round 2 with 12 Premiership clubs also joining the competition. The final 8 Premiership clubs (who are competing in Europe) join in round 3.
Denis Smith told the official website
"The draw was seeded, so we always knew that in all likelihood it would be a tough tie. But to face Wednesday at their own ground is not one we would have picked for ourselves.
"That is the draw though and a visit to Hillsborough is always one the players look forward to.
"It's also not too far for our supporters to travel, even for a midweek fixture, so I would hope for a good following."
Full draw
| Northern Section Chesterfield | v | Wolverhampton Wanderers |
| Stoke City | v | Darlington |
| Port Vale | v | Preston North End |
| Burnely | v | Hartlepool |
| Sheffield Wednesday | v | Wrexham |
| Bury | v | Sunderland |
| Hull City | v | Tranmere Rovers |
| Blackpool | v | Barnsley |
| Huddersfield Town | v | Mansfield Town |
| Carlisle United | v | Bradford City |
| Rotherham United | v | Oldham Athletic |
| Scunthorpe United | v | Lincoln City |
| Accrington Stanley | v | Nottingham Forest |
| Grimsby Town | v | Crewe Alexandra |
| Leeds United | v | Chester City |
| Doncaster Rovers | v | Rochdale |
| Stockport County | v | Derby County |
| Leicester City | v | Macclesfield Town |
| Southern Scection Cardiff City | v | Barnet |
| Milton Keynes Dons | v | Colchester United |
| Swindon Town | v | Brentford |
| Crystal Palace | v | Notts County |
| Hereford United | v | Coventry City |
| Swansea City | v | Wycombe Wanderers |
| Peterborough United | v | Ipswich Town |
| AFC Bournemouth | v | Southend United |
| Brighton & Hove Albion | v | Boston United |
| Cheltenham Town | v | Bristol City |
| Millwall | v | Gillingham |
| Southampton | v | Yeovil Town |
| Birmingham City | v | Shrewsbury Town |
| Plymouth Argyle | v | Walsall |
| Bristol Rovers | v | Luton Town |
| Queens Park Rangers | v | Northampton Town |
| Torquay United | v | Norwich City |
| Leyton Orient | v | West Bromwich Albion |